Pathway
Resolution
Identify the pathways driving disease and distinguish them from adaptive or compensatory biology.
BioGPU
Where AI Runs to Resolve Biology
Causal biology resolved across the discovery lifecycle
Understand the causal biology driving disease,
the function of targets,
and the effects of compounds.
Target
Resolution
Understand what targets do, how they are regulated, and how they influence disease biology.
Compound
Resolution
Explain what compounds do in biology, why they succeed or fail, and how resistance emerges.
The biology runtime for AI.
BioGPU enables AI models to reason inside cells through massive parallel visual biology experiments.
BioGPU Agent
BioGPU Runtime
Massive parallel visual biology experiments
Visual Biology Tokens
-
Protein
localization -
Nuclear
translocation -
Phospho-
signaling -
Cytoskeletal
dynamics -
Mitochondrial
state -
RNA
granules -
Protein
interactions
1000+
Experiments at each iteration
Cells
Millions of cells across diseases,
conditions and perturbations
conditions and perturbations
Visual Biology Tokens
FRONT: THE STATEMENT
Textual statement of biological activity
VB-0001
SOD1 is abnormally enriched in the nucleus.
VB-0002
P-TDP-43 accumulates strongly in both cytoplasm and nucleus.
VB-0003
4EBP1 is phosphorylated across both nuclear and cytoplasmic compartments despite unchanged levels.
VB-0004
SRSF2 is strongly upregulated in the nucleus.
front
VISUAL BIOLOGY TOKENS
THOUSANDS OF TOKENS
produced per experiment
Across pathways, cell types, conditions and diseases
back
BACK: THE EVIDENCE
Dynamic visual evidence (Healthy vs Disease)
SOD1
H
D
P-TDP-43
H
D
4EBP1 (p)
H
D
SRSF2
H
D
Visual Biology Tokens enable AI agents to reason inside biology at scale
Introducing
Experimental reasoning inside cells
BioGPU enables AI models to design experiments, observe real cellular responses, and reason causally within the complexity of living systems.
- Design hypotheses
- Run visual biology experiments
- Observe real cellular outcomes
- Iterate and refine understanding
- Resolve biology causally
Visual Biology Tokens
Foundational
pathway-image-to-text model
Converting visual biology into language AI can reason about.
PATHWAY IMAGES
Visual representations of biological reality
-
Protein
localization -
Nuclear
translocation -
Phospho-
signaling -
Cytoskeletal
dynamics -
RNA
granules -
Mitochondrial
state -
Protein
interactions -
Pathway
responses
FOUNDATIONAL MODEL
Pathway-image-to-text
Trained on 2B+ pathway visualizations across 140 cell types and 25 diseases
TEXTUAL BIOLOGICAL STATEMENTS
Biological facts extracted from images
TDP43 accumulates in the cytoplasm.
mTOR signaling is hyperactivated.
Mitochondrial fragmentation increases.
RNA granule formation is enhanced.
Protein co-localization increases under perturbation X.
Nuclear translocation of TFs is enriched under condition Y.
BioGPU Agent
Chat with cells.
Experimentally resolving the biology of
pathways, targets, and compounds.
BioGPU Runtime
Massive parallel visual biology experiments
The Biology Resolution Loop
Design, run and analyze visual biology experiments
BioGPU Runtime
executes visual biology experiments inside cells.
Visual Biology Tokens
The language that connects AI and biology.
Think
Plan
Execute
Learn
BioGPU RESOLUTION AGENT
BioGPU RUNTIME
MORE EXPERIMENTS
MORE UNDERSTANDING
MORE RESOLUTION
Scaling up disease resolution
EARLY UNDERSTANDING
Sparse, disconnected insights
Millions of visual biology experiments.
Millions of biological observations.
Building causal understanding.
Millions of biological observations.
Building causal understanding.
RESOLVED NETWORK
Deep, causal understanding
BioGPU Agent - Driving the BioGPU runtime
BioGPU agent executes on the BioGPU runtime to resolve causal biology in ALS and discover novel targets
Biology
Resolved
BioGPU connects AI directly to large-scale biological experimentation, transforming millions of cellular observations into causal biological understanding.
TARGET BIOLOGY RESOLVED
Understand which targets matter, why they matter, and when they matter.
COMPOUND BIOLOGY RESOLVED
Understand mechanism of action, toxicity, resistance, and therapeutic potential.
DISEASE BIOLOGY RESOLVED
Understand the causal mechanisms and pathway architecture driving disease.